Benefits of nicotinamide riboside molecule in skin and protection against aging
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the product Activate It contains the active ingredient nicotinamide riboside.
Nicotinamide riboside is a new generation of vitamin B3 that is used in the body +NAD is converted. +NAD is an auxiliary molecule found inside every cell that supports many aspects of health as we age.
However, the quantity +NAD in the body naturally decreases with age. Activate As one of the precursors +NAD effectively increases the level of this molecule in the body.
The facts have shown that the level increases +NAD may help reverse the signs of aging and reduce the risk of many chronic diseases.
Continue to examine skin aging, skin cancer and positive effects Activate We will pay in this process.
Skin aging includes a decrease in various biological functions as well as a change in appearance. In the field of cosmetics and beauty, skin aging is divided into two categories and studied:
- Natural aging, which is a skin change over time and caused by internal factors of the body.
- Photoaging is a skin change caused by exposure to the sun’s ultraviolet rays.
Natural aging and aging under the influence of light are not exclusively separate and overlap to some extent. Clinical observations show that skin that has aged naturally is thin, dry and has many fine lines, while skin that has aged under the influence of light usually has a leathery and loose appearance with reduced elasticity, uneven pigmentation, wrinkles. Big and deep and the appearance of blood vessels is accompanied. A decrease in the level of substances such as collagen and elastin among skin cells is constantly observed in natural aging or aging under the influence of light.
Reactive oxygen species and free radicals are small, unstable and highly reactive molecules that can damage proteins, lipids (fats) and DNA (genetic material) of cells. The production of these molecules in cells caused by external factors, such as ultraviolet rays and pollution, or internal metabolic (fuel) dysfunction, can cause oxidative damage (inability of the cell to neutralize and inhibit toxic mediators or repair damage) to become cells Also, reactive oxygen species cause premature aging of the skin. In fact, active oxygen plays a harmful role in causing various skin diseases and cancer. Therefore, substances that directly remove this type of oxygen or increase the antioxidant capacity of cells are expected to help maintain a stable skin condition.
In addition, skin immunity, which is a key defense against the spread of various types of skin cancer, is suppressed by even small doses of UV radiation. Therefore, preventing this suppression can reduce the incidence of skin cancer.
Shortage +NAD leads to skin sensitivity to UV rays, disrupts the DNA damage response and repair process, and increases the risk of cancer. In addition, reducing the level +NAD has been linked not only to human skin aging but also to cancer.
Today, despite the use of sunscreens, the incidence of skin cancer is still increasing. Sunscreens can prevent sunburn while allowing immune suppression. Also, the effectiveness of sunscreens is limited due to the frequency and volume of application that is less than optimal.
Additionally, there is growing concern about the adverse effects of sun avoidance and sun protection. Vitamin D deficiency, which is remarkably common in the general population, is associated with an increased risk of autoimmune, cardiovascular, malaise, and osteoporosis. Therefore, there is a need for auxiliary photoprotective agents that do not compromise vitamin D levels, can be taken orally to improve adherence, are safe, and are available.
Based on this, the level-up strategy +NAD could be a promising approach for skin cancer prevention.
In the field of skin, many studies on the positive role of precursors +NAD has been used in the prevention and treatment of cancer, disorders that lead to the appearance of blisters on the surface of the skin, some skin diseases, wound healing and pigment disorders.
In these studies, the precursor +NAD:
- It reduces skin oxidative damage and inflammatory response caused by ultraviolet rays and restores antioxidants in blood and skin tissue.
- It can improve the stability of skin surface and biological energy in aged and stressed cells.
- In the cell culture medium, it increases the lifespan of the cells in the middle part of the skin.
- Strengthening the synthesis of skin collagen, inhibiting its destruction and increasing cell proliferation, and also increases wound healing in laboratory conditions.
Therefore, using a safe oral supplement, along with other protective methods, can be an ideal method to prevent the harm caused by the sun on the skin. Using a precursor +NAD-like Activate It prevents the reduction of cellular energy caused by ultraviolet rays and accelerates DNA repair. This precursor reduces the risk of skin cancer and prevents the immunosuppressive effects of UV rays. Therefore, it can have beneficial effects against skin aging changes and tumor progression.
supplement Activate Having these conditions, it is useful as an essential nutrient for the health of the whole body and skin.
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