Dapoxetine, a review of the benefits and side effects of Dapoxetine

Today, issues related to mental and sexual health, including sexual disorders, have received a lot of attention as one of the most important and vital cases in medical science and psychology. One of the common sexual disorders that has a great impact on people’s lives is delayed ejaculation (DE) or, more precisely, “delayed ejaculation”. With its mechanism of action, Dapoxetine will help a lot to control ejaculation and increase intercourse time. In the following, we will examine the mechanism of action, pharmaceutical forms, uses, methods of use, precautions and contraindications of Dapoxetine.

Dapoxetine dosage forms

Dapoxetine is marketed under the brand name Priligy and is available in 30 and 60 mg packs. This drug is approved by the US Food and Drug Administration (FDA). Drugs of the same group of this drug include citalopram, S citalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, etc.

Uses of dapoxetine tablets

The term premature ejaculation is used when a man reaches orgasm (ejaculates) faster than he or his partner would like. For some men it may be temporary and get better on its own. Dapoxetine is a selective serotonin reuptake inhibitor drug specifically developed for the treatment of premature ejaculation. This drug increases ejaculation time and can improve ejaculation control. This medicine starts to work in the body at a high speed, so you must have a correct prediction of the intercourse time.

Pharmacological effects and mechanism of action of Dapoxetine

This drug belongs to the category of antidepressants and short-acting serotonin reuptake inhibitors, which increases the control over ejaculation by prolonging the time and works at a high speed.

Dosage of Dapoxetine

Before taking Dapoxetine, check the drug information on the drug package. The manufacturer has explained the exact usage method for you. The information on the drug package will give you more information about dapoxetine, as well as a complete list of side effects you may experience from taking it. Take this medicine exactly as your doctor has told you. At the same time as taking the pill, drink a full glass of water. The recommended initial dose of this pill is 30 mg, which is taken 1 to 3 hours before sexual intercourse. Your doctor may also decide to increase your dose to one 60 mg tablet.

Time to take dapoxetine tablets

Your doctor will prescribe you a higher dose only if the 30 mg dose is not enough and you have not experienced any side effects such as fainting. Dapoxetine is not intended for regular daily use and you should only take it before sex. The pill tastes bitter, so swallow it whole without chewing. Be careful that the best dosage for you is prescribed by your doctor, so it is better to take the medicine with the doctor’s approval and consultation.

Precautions

1. After prescribing the use of this medicine, see your doctor regularly so that he can increase or even stop the use of the medicine if necessary. If you develop certain side effects, your doctor should prescribe similar drugs for you. Also, if you notice any dangerous side effects, inform your doctor if you use it without a prescription.
2. Avoid drinking alcohol after using dapoxetine, because alcohol will make you drowsy and dizzy, and taking these two at the same time will increase the sedative effects of alcohol.
3. Do not use any recreational drugs while taking dapoxetine, as they may cause serious side effects.
4. There is a chemical in grapefruit juice that can increase the amount of dapoxetine in your bloodstream and cause dangerous side effects. If you drink grapefruit juice, do not take dapoxetine for at least 24 hours afterward.
5. This medicine causes confusion and drowsiness in some patients after a while, avoid doing things that require high alertness (including driving, working with heavy machinery, working with tools, etc.).
6. Some medicines are not suitable for people with certain conditions and sometimes medicines can only be used with extra care. For these reasons, before starting Dapoxetine, consult your doctor regarding specific medical history such as fainting, heart disease, bleeding or coagulation disorder, mental health, kidney or liver disorders, etc.

Dapoxetine contraindications

1. A history of sudden loss of consciousness
2. History of dizziness caused by low blood pressure
3. Kidney disorders
4. Specific sexual disorders
5. physical weakness
6. Heart problems (such as heart failure or irregular heartbeat)
7. Glaucoma (increased eye pressure)
8. Liver disorders
9. Unexplained bleeding or blood clotting disorder
10. Immune deficiency, infection or susceptibility to infection
11. Lactose intolerance
12. Allergy to this drug or its ingredients
13. Neurological diseases (such as bipolar disorder, depression or mania)
14. epilepsy

Dapoxetine side effects

Dizziness and headache, drowsiness, light-headedness, mood changes (such as doubting, feeling depressed or suicidal thoughts), low blood pressure and fainting, fatigue, feeling weak, numbness, tremors, etc. are some of the side effects of Dapoxetine tablets. (Dapoxetine). If any of these effects persist or worsen, tell your doctor or pharmacist right away. Most drugs, in addition to their beneficial effects, can cause unwanted side effects. It should be noted that many people who take this drug do not have serious side effects, but its excessive use is not recommended.

1. blurred vision
2. Abnormal heartbeat
3. Headache and dizziness
4. Ringing in the ears
5. Stomach ache and benefit
6. Feeling sick (nausea and vomiting)
7. diarrhea
8. nasal congestion
9. lightheadedness
10. Drowsiness
11. Orthostatic pressure drop
12. Drop in blood pressure and passing out
13. Excessive sweating

Dapoxetine drug interactions

1. Concomitant use: MAOI, antidepressants, thioridazine, lithium, linezolid, tryptophan, tramadol, migraine treatment drugs
2. Drug interactions (use only with doctor’s approval): nerve depressants, nonsteroidal anti-inflammatory drugs (NSAIDs), anticoagulants such as warfarin, other ejaculatory drugs such as sildenafil and tadalafil, antihypertensives such as verapamil, dilitazem, antifungals such as fluconazole Antibiotics such as erythromycin, clarithromycin, anti-nausea aperpitant

Dapoxetine use during pregnancy and breastfeeding

Dapoxetine drug is in group C of the risks of use during pregnancy, that is, it can be used under the supervision and review of a doctor. This drug is a serotonin reuptake inhibitor (SSRI) used to treat premature ejaculation. Dapoxetine can cause serious side effects, including heart disorders, neurological disorders, developmental delay, etc. in the fetus. In animal studies, many cases of side effects have been observed in the fetus. The benefits of the drug against possible risks determine the use or non-use of this drug during pregnancy.

Dapoxetine storage conditions

Dapoxetine should be stored at room temperature and away from light. It is also important to keep all medications out of the reach of children, as many forms of medication (such as weekly tablets and eye drops, creams, patches, and inhalers) are not child-resistant and can be easily opened by young children. . Unnecessary medications should be disposed of in specific ways to ensure that pets, children, and other people cannot ingest them.

Dapoxetine last word

In general, as we described in this article from the online pharmacy magazine of Positive Green, dapoxetine as one of the drugs used in the treatment of late ejaculation disorder can have a positive effect on the sexual relationship of people, but it should be done with the doctor’s consultation and along with psychological strategies in order to Complete and permanent improvement of the condition of the people in question should be prescribed. Although this drug can provide a temporary improvement in the control of ejaculation time, psychological solutions and emotional counseling are also very important as one of the treatment components. People with late ejaculation disorder should deal with their problems with professional support during the treatment process and find permanent solutions to improve their sexual and emotional relationships.