Examining the uses and side effects of Diprocol ointment (Diprocol)
Diprocol ointment is a topical medication used to treat inflammation and pain in skin conditions such as eczema, psoriasis, and sunburn. This product consists of two active substances Clotrimazole and Betamethasone. As one of the main types of medicines and skin products, ointments are especially important for treating skin problems.
In addition to providing effective treatments for skin problems, ointments are also effective in relieving the symptoms of allergies and itching and help improve people’s quality of life. Join us to find out more about the details of Diprocol ointment in the field of skin health.
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Diprocol dosage forms
Pharmacies produce their products in medicinal forms such as tablets, capsules, syrups, serums, injectable solutions, etc. The doctor prescribes the best forms of medicine according to the physical conditions, medical records and age of the patient (adults, children and the elderly). Diprocol dosage forms include cream color 0.05%, 1% (15 g, 45 g) and lotion 0.05%, 1% (30 ml).
Uses of Diprocol
Diprocol cream or ointment is used to treat cutaneous candidiasis or dermatophytosis, vaginal candidiasis, superficial skin infection, etc. The main uses of this product are those that can be used with the approval and prescription of a doctor. It should be noted that some doctors also prescribe this medicine for the treatment of tinea cruris (bug itch), tinea corporis, tinea pedis (athlete’s foot fungus), treatment of genital psoriasis, treatment of mild fungal infections with itching, etc. The uses of this ointment are very wide, but it needs to be seen and examined by a dermatologist so that the best treatment can be prescribed for you.
Pharmacological effects and mechanism of action of Diprocol drug
The presence of betamethasone in Diprocol drug compounds reduces inflammation by stabilizing leukocyte lysosomal membranes. Clotrimazole also binds to the phospholipids of the fungal cell membrane, which changes the permeability of the cell wall and leads to the loss of intracellular elements.
Dosage of Diprocol ointment
The consumption of Diprocol ointment depends on the type of disease or inflammation, location and location of the disease, medical history, age, etc. Usually, this cream is prepared thinly on the affected skin area and gently massaged. The frequency of use and the duration of use usually depend on the doctor’s advice, and the doctor’s instructions should be followed exactly.
Do not change the dosage of the ointment or change the medicine without a doctor’s order because it may cause side effects or other problems. For any questions or concerns about the dosage of Diprocol, consult your doctor or dermatologist.
Time to use Diprocol cream
The amount and time of use of Diprocol cream is stated in the drug information available in the product packaging. The manufacturer has included the amount and method of general consumption for you. This product can also be used in children and the elderly, but its use in the elderly requires the approval and comprehensive examination of a dermatologist. If the elderly and babies use this ointment without a doctor’s prescription, the possibility of serious side effects and skin problems will be high.
Dosage of Diprocol ointment in adults
- For general use, the amount and time of consumption are clearly mentioned on the product packaging.
- To treat Tinea Cruris & Tinea Corporis (fungal infection), use Diprocol cream on the infected area every 12 hours for 1 week. If there is no clinical improvement, after 1 week it should be re-evaluated by the doctor. Also, the duration of treatment is 2 weeks and the total dosage should not be more than 45 mg per week.
- Apply Diprocal Lotion to the infected area every 12 hours for 1 week to treat Tinea Cruris & Tinea Corporis. If there is no clinical improvement, re-evaluate after 1 week.
- Diprocol ointment for Tinea Pedis (a common type of fungus) is prescribed on the infected area every 12 hours for 1 week. If there is no clinical improvement, after 1 week it should be re-evaluated by the doctor. The duration of treatment is 2 weeks and the total dosage should not be more than 45 mg per week.
- Apply Diprocal Lotion for Tinea Pedis (a common type of fungus) to the infected area every 12 hours for 1 week. If there is no clinical improvement, re-evaluate after 1 week. The duration of the treatment is 2 weeks and the total consumption should not be more than 45 ml per week.
Precautions
On the packaging of the product, the usages, amount and time of usage, precautions and contraindications are clearly stated. Pregnant women and lactating mothers should consult their doctor regarding possible side effects and risks before use. Long-term use of Diprocol cream or ointment will cause side effects in pregnant women and infants.
It is also necessary to avoid using Diprocol ointment in sensitive areas of the skin such as the face, eyes, lips, and areas affected by hands and feet. If you need treatment in these areas, follow your doctor’s advice.
- Do not use an occlusive dressing after using the ointment. Systemic absorption of topical corticosteroids may cause hypercortisolism or suppression of the hypothalamic, pituitary, and adrenal axis.
- Long-term treatment with corticosteroids associated with the development of Kaposi’s sarcoma is dangerous.
- Occlusive dressings, prolonged use, application to bare skin or large surfaces may increase absorption and lead to hyperglycemia, glycosuria, or Cushing’s syndrome.
- It is not used to treat diaper dermatitis in any age group. Significant side effects associated with corticosteroids have been reported.
- The use of topical corticosteroids may increase the risk of posterior subcapsular cataracts and glaucoma. Cataracts and glaucoma have been reported in postmarketing experience with topical corticosteroid products, including betamethasone topical products.
- Using this product in the eyes can lead to blurred vision, burning, pain, etc. In case of eye contact, advise patients to report any visual symptoms and see an ophthalmologist for evaluation.
- Pregnant women and lactating mothers should take this medicine with the doctor’s prescription. Because it may be dangerous for the baby or fetus.
- Long-term use of Diprocol ointment may have serious side effects such as thinning of the skin, cracking of the skin and increased risk of infection.
Diprocol contraindications
- Documented hypersensitivity
- Pregnant women and children (doctor’s prescription)
- Allergy to any of the components of this ointment (clotrimazole and betamethasone).
Diprocol side effects
Burning, pain, skin infection, dry skin, localized burning, edema, urticaria, skin atrophy, secondary infection, skin wound, acne-like eruption, etc. are some of the side effects of Diprocol ointment or cream. If any of these effects persist or worsen, tell your doctor or pharmacist right away. Most people who use this drug do not experience serious side effects. However, if serious side effects occur, stop taking the drug and consult a doctor.
- dry skin
- paresthesia
- Local burning
- human
- urticaria
- Atrophy of the skin
- Secondary infection
- skin ulcer
- Acne-shaped eruption
- a bruise
- folliculitis
- stretch marks
Diprocol drug interactions
Drug interactions may change how your medications work or increase your risk of serious side effects. Patients should prepare a list of chemical and herbal medicines they use and show it to the doctor when they visit. Do not start, stop, or change any medication without your doctor’s approval. Diprocol ointment is a combination of clotrimazole and betamethasone, so it is important to check the drug interactions of these 2.
Aldesloquine, progesterone, corticorelin, hyaluronidase, deferasirox, ritodrine, sirolimus, tacrolimus (systemic) drugs, etc. cause some changes and drug interactions with this drug.
Taking Diprocol during pregnancy and breastfeeding
There are no data on the use of topical betamethasone dipropionate or clotrimazole in pregnant women to determine the risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes. Observational studies show an increased risk of low birth weight infants with the use of strong or very strong topical corticosteroids during pregnancy. Advise pregnant women that treatment may increase the risk of low birth weight infants. Use the medicine in the smallest area of the skin and in the shortest possible time.
Animal data on Diprocol drug use
- In an animal reproduction study, betamethasone dipropionate caused malformations (eg, umbilical hernia, cephalocele, and cleft palate) in pregnant rabbits when administered intramuscularly during organogenesis.
- The available data do not permit the calculation of relevant comparisons between the systemic exposure of clotrimazole and betamethasone dipropionate observed in animal studies with the systemic exposure expected in humans after topical administration of the drug.
The effect of Diprocol ointment on breastfeeding
Advise nursing mothers to use the medicine in the smallest area of the skin and for the shortest possible time during breastfeeding. Also, breastfeeding mothers are advised not to apply the medicine directly on the nipple and areola so that the baby is not at risk when consuming milk directly.
Diprocol storage conditions
Diprocol should be stored at room temperature (preferably cool) away from light and moisture. Keep all chemical and herbal medicines out of the reach of children and animals. Dispose of this product properly when it has expired or is no longer needed. Avoid pouring all kinds of medicines into the toilet well, street and sewer.
The last word about Diprocol ointment
As we said in this article from Positive Green Pharmacy magazine, Diprocol ointment is widely used in the treatment of cutaneous candidiasis or dermatophytosis, vaginal candidiasis, superficial skin infection, etc. In general, Diprocol ointment is extremely effective and vital as one of the key drugs in the treatment of skin problems.
Due to its positive effects in reducing inflammation and relieving skin symptoms, this ointment allows people who are facing skin problems to experience a healthier and more comfortable life. However, it is very important to have the expert assistance of skin health specialists and to strictly follow the instructions for its use in order to avoid side problems and obtain positive results.
Site source: Medscape