What is bisacodyl? – Green positive pharmacy magazine

Constipation is one of the annoying diseases in health center visitors, which is caused by various reasons. One of the new drugs that has attracted a lot of attention in this field is bisacodyl tablets. In this article, we intend to comprehensively review the benefits and possible side effects of bisacodyl tablets and examine its uses in the management of some abdominal and intestinal problems. Also, we will have a look at the recent research and the results obtained in connection with this drug so that the readers have the most up-to-date information in this field.

Pharmaceutical forms of bisacodyl

Pharmaceutical forms of Bisacodyl are available in the market under domestic and foreign brands or under the brand name of different companies. This drug is found in pharmacies in the form of regular tablets in delayed release of 5 mg and suppositories. Pharmaceutical companies produce drugs in different pharmaceutical forms according to the needs of patients and doctors. In any case, the use of drugs should be done only with the prescription of a doctor and under his supervision. Each medication may have its own side effects and drug interactions, so it is important to consult your doctor before taking any new medication.

Uses of bisacodyl tablets

The most important use of bisacodyl tablets is to treat constipation. Despite this pill and its excellent effect on the treatment of constipation, it is suggested to use milder products (such as oral laxatives) to treat this condition as much as possible. This drug is a stimulant laxative that works by increasing the amount of fluid or salt in the intestines, this effect usually leads to a bowel movement in 15 to 60 minutes. Constipation can be treated by drinking plenty of fluids (four to six 8-ounce glasses per day), eating high-fiber foods, and exercising regularly. The use of this product in children under 6 years is not recommended, unless prescribed by a doctor.

Pharmacological effects and mechanism of action of bisacodyl tablets

The mechanism of action of bisacodyl tablets or suppositories stimulates the smooth muscle of the intestine and possibly the inner plexus of the colon, thereby increasing peristalsis. As a result, by changing the secretion of water and electrolytes, the accumulation of intestinal fluid will cause it to relax. Bisacodyl 10 suppository or bisacodyl 5 suppository directly affects the intestine and causes fluid retention and as a result the stool loosens for excretion.

Dosage of bisacodyl suppositories

Be sure to wash your hands before using bisacodyl suppositories. If the suppository is too soft to insert, refrigerate for 30 minutes or run cold water over it before removing the foil cover. Then remove the foil cover of the suppository, if desired, the suppository can be moistened with lukewarm water. Patients should never use mineral oil or vaseline to soften suppositories. Because doing so may reduce the effectiveness of the product. Next, lie on your left side and bend your right knee a little. Gently insert the suppository with the pointed end towards the navel and into the rectum.

Time to use bisacodyl suppositories

After inserting the suppository into the anus, if possible, stay in your position for 15 to 20 minutes until you feel the urge to defecate. If this product is used excessively, it may cause loss of normal bowel function and inability to defecate. The time of taking bisacodyl suppositories or tablets should be determined by the doctor. If you notice symptoms of overdose such as diarrhea, abdominal pain, weight loss, or weakness, contact your doctor immediately. Discontinue use if you do not have a bowel movement after using this product or if you think you may have a serious medical problem.

Precautions

Before using bisacodyl, tell your doctor or pharmacist if you are allergic to it. This product may contain inactive ingredients that can cause allergic reactions or other problems. If needed to treat constipation, laxatives should only be used temporarily. High doses or frequent use can lead to persistent constipation and laxative dependence. When visiting the doctor, inform him of your medical history, including intestinal problems (such as obstruction, ulcerative colitis, hemorrhoids, rectal bleeding), current stomach or abdominal symptoms (such as nausea or vomiting, pain, muscle cramps, etc.).

1. Strictly avoid continuous use of this drug, as it may cause laxative dependence.
2. Do not use in patients with gastroenteritis.
3. Do not chew the tablet of this product, swallow it whole with water or food.
4. It is not allowed to consume antacid or milk within 1 hour after consumption.
5. This medicine is not recommended for children under 6 years of age due to the need to swallow pills.
6. Some dosage forms may contain benzyl alcohol, which has been associated with fatal toxicity in infants. Avoid dosage forms containing benzyl alcohol derivatives in infants.

Contraindications for bizacodil tablets

Before using and consuming different drugs, first read the drug information on the product well. Most of the chemical and even herbal medicines available in the market have precautions and contraindications. In this regard, strictly avoid using bisacodyl without a prescription. Patients should inform their doctor if they are already taking certain medications to avoid the risks of drug interactions. Some of the most important contraindications for this drug include the following:

1. Hypersensitivity
2. Obstruction or severe obstruction
3. Symptoms of appendicitis or acute surgical abdomen
4. Vomit
5. Bleeding from the rectum

Bisacodyl side effects

Irritation, burning, rectal itching, mild discomfort, abdominal cramps, or nausea may occur after taking bisacodyl tablets or suppositories. If any of these effects persist or worsen, tell your doctor or pharmacist right away. If your doctor has prescribed this medication based on your specific medical history, remember that he or she has determined that the benefits to you outweigh the risk of side effects. Many people who use this product do not have serious side effects, but over-the-counter and continuous use is not allowed.

• Electrolyte and fluid imbalance
• Excessive diarrhea
• nausea
• Rectal burning
• dizziness
• Vomit

Dangerous side effects of Bisacodyl

Tell your doctor right away if you have any serious side effects. Some of the most important side effects of bisacodyl tablets include severe diarrhea, rectal bleeding or blisters, severe diarrhea leading to dehydration, seeing signs of dehydration, unusual decrease in urination, unusual dry mouth or increased thirst, lack of tears, dizziness or lightheadedness, paleness and wrinkles. It is skin. A very serious allergic reaction to this drug is rare. However, see a doctor right away if you have signs of a serious allergic reaction, including skin rash, itching or swelling (especially of the face, tongue, and throat), severe dizziness, and trouble breathing.

Bizacodil drug interactions

Drug interactions may change how your medications work or increase your risk of serious side effects. Before going to the doctor, patients should prepare a list of chemical and herbal products they use and show it to the doctor. Your doctor prescribes the desired drugs according to your physical condition, medical records and age, and also prevents drug interactions and dangerous side effects by considering the drugs used. Some products that may interact with this drug include laxatives (including castor oil, stool softeners, lubricants such as mineral oil).

Taking bisacodyl tablets during pregnancy and breastfeeding

Pregnant women should strictly refrain from taking different medicines unnecessarily and without a doctor’s order. Plasma concentrations of the active metabolite of BHPM are low after doses of 10 mg/day for 7 days. Short-term use is generally considered safe in pregnancy. Although no specific risk of this product has been reported for pregnant women, avoid long-term use of this product. Also, no effects of the drug have been observed in the milk of mothers who took 10 mg of this pill per day for 7 days.

1. In general, the use of bisacodyl (bisacodyl) in pregnant women can be used with a doctor’s order, controlled studies in pregnant women do not show evidence of fetal risk.
2. Animal studies in connection with the use of this drug do not show any risk.
3. If the benefits are greater than the risks, pregnant women can take the medicine by following the dosage and method of administration.
4. It can be used in emergency situations where the use of medicine is necessary for pregnant women and there is no safer medicine available.
5. However, pregnant women are suggested to use alternative drugs available in the market to reduce the risk of side effects on the mother and fetus.

Bisacodyl tablet storage conditions

Refer to the storage information on the product label. Keep this product out of the reach of children and animals, and of course away from heat, humidity and sunlight. Avoid pouring various medicines into the street, toilet and sewer. Dispose of this product properly when it has expired or is no longer needed.

The last word of bisacodyl medicine

Constipation, as a common problem in the digestive system, can cause unpleasant complications for those who experience it. Considering the important role of the digestive system in the process of digestion and absorption of food, any disturbance in the movement and emptying of feces can lead to a delay in the absorption of nutrients and the optimal performance of the functions of the digestive system.

As we explained in this article from Positive Green Pharmacy magazine, bisacodyl tablets and suppositories will reduce intestinal problems and constipation in the patient with its mechanism of action. Finally, awareness of constipation prevention and management methods is very important. Proper nutrition, drinking enough water, regular physical activity and, if necessary, consultation with a doctor in choosing the right medicines can help control and improve the condition of constipation.

Site source: Medscape

Frequently asked questions about Bisacodyl