What is Megacort ointment?

Megacort ointment is known as one of the best products in the field of skin care and treatment of skin problems. With its special ingredients, this ointment has been able to help millions of people around the world to improve their skin problems. Mometasone Ointment is not only an ordinary skin care product, but also one of the best-selling and most trusted treatment products for skin problems such as skin inflammations, itching, eczema, and skin rashes. Due to the compounds in it, this ointment helps to improve and relax people’s skin and can be used for various purposes, including the treatment of eczema to the relief of small burns.

Pharmaceutical forms of Megacort

Domestic and foreign pharmaceutical companies produce their products in medicinal forms such as tablets, syrups, serums, injectable solutions, capsules, ointments, etc. The doctor prescribes different types of these drugs according to the physical conditions, medical records and age of the patient (adults, children and the elderly). Megacort drug is available in pharmacies in the form of cream, lotion, ointment 0.1% and nasal spray suspension 50 micrograms. The doctor should prescribe different types of these products according to the type of inflammation and taking into account the age of the patient, in order to have the least side effects along with the maximum benefit.

Uses of Megacort Ointment

Megacort ointment is used to treat skin diseases such as eczema, psoriasis, allergies and skin rashes. Mometasone (another name for Megacort Ointment) is a moderate-strength corticosteroid that can also reduce swelling (inflammation), itching, and redness. Some of the most important uses of ointment and nasal spray of this product include inflammatory hyperkeratosis dermatosis, inflammation and itching related to dermatosis, seasonal allergic rhinitis (spray), nasal polyps (spray), etc. The doctor should consider the condition of the patient and the type of inflammation and prescribe the best medicine (ointment, cream and spray) for him.

Use of mometasone ointment in adults

1. Inflammatory hyperkeratosis dermatosis
2. Inflammation and itching associated with dermatosis
3. Seasonal allergic rhinitis (spray)
4. nasal polyps (spray)

Use of mometasone ointment in children

1. Seasonal allergic rhinitis (spray)
2. nasal polyps (spray)
3. Allergic rhinitis (spray)
4. Inflammatory hyperkeratosis dermatosis

Pharmacological effects and mechanism of action of mometasone ointment

Corticosteroid with strong anti-inflammatory properties; It affects various cells including mast cells and eosinophils. It also affects inflammatory mediators (such as histamine, eicosanoids, leukotrienes, cytokines). Minimal systemic absorption of mometasone occurs mainly with the small amount swallowed during nasal administration.

Dosage of mometasone

Before taking any medication, read the medication information on its package carefully. The amount and time of use for general use are mentioned on the product, however, the best way to use is to prescribe a doctor’s prescription. Megacort (Mometasone) ointment is for use on specific areas of the skin only, it is not recommended for use on the face, groin, armpits or for diaper rash (unless directed by a doctor).

Before use, wash and dry your hands and the desired area of ​​the body. Apply a thin layer of the medicine to the affected area once a day, usually as directed by your doctor. Also, do not cover the treated area with a bandage or other dressings, unless your doctor has prescribed it.

Dosage of Megacort ointment in adults

1. Inflammatory hyperkeratosis dermatosis: apply cream, lotion or ointment once a day depending on the doctor’s prescription on the affected area.
2. Inflammation and itching associated with dermatosis: Consult your doctor or pharmacist for treatment.
3. Allergic Rhinitis: The spray of this drug is used for nasal symptoms of allergic rhinitis. The recommended dose is 2 sprays (100 micrograms) in each nostril per day.
4. Seasonal allergic rhinitis: The use of mometasone spray for seasonal allergic rhinitis is also recommended for the prevention of seasonal allergic rhinitis. The recommended dose is 2 sprays (100 micrograms) in each nostril per day. To prevent allergies, 2 sprays (100 micrograms) in each nostril per day 2 to 4 weeks before the desired season are recommended.
5. Nasal polyps: The spray of this product is recommended to control nasal polyps: 2 sprays (100 micrograms) in each nostril every 12 hours.

Dosage of mometasone in children

1. Inflammatory hyperkeratosis dermatosis: safety and effectiveness of this drug in children less than 2 years have not been proven. For children 2 years and older, apply cream, lotion or ointment to the affected area during the day.
2. Allergic rhinitis: 1 spray (50 micrograms) in each nostril per day for children 2 to 12 years old and 2 sprays (100 micrograms) per nostril per day for people over 12 years old is recommended to reduce the nasal symptoms of allergic rhinitis.
3. Seasonal allergic rhinitis: nasal congestion with seasonal allergic rhinitis; It is also used to prevent seasonal allergic rhinitis in children. The dosage for children 2 to 12 years old is 1 spray (50 micrograms) in each nostril per day and for people over 12 years old, 2 sprays (100 micrograms) per nostril per day.

Time to use Megacort ointment

Wash your hands with soap and water after each use of mometasone ointment or spray, unless you have used this medicine to treat your hands. Use this ointment regularly to get the most benefit from it. It is not allowed to use large amounts of this product’s ointment or spray, because if you use a lot, the speed of healing your inflammation and disease will not increase and will only cause complications. Tell your doctor if your condition does not improve or worsens after 2 weeks of treatment.

Precautions

Before using Mometasone or Megacort ointment, carefully check the precautions and contraindications on the product packaging. In case of sensitivity or allergy to any of the medicinal ingredients of this product, do not use the medicine. This product may contain inactive ingredients that can cause allergic reactions or other problems.

Consult your doctor if you have medical history such as poor blood circulation, diabetes, immune system problems, skin infections, etc. According to your medical records, if necessary, the doctor will change the prescription and prescribe similar drugs for you.

1. The safety and effectiveness of Megacort ointment or spray for long-term use in children has not been proven. In this regard, pediatric patients may be more susceptible to systemic toxicity.
2. Do not use occlusive dressings after using ointment, cream or spray.
3. In case of simultaneous skin infections, use appropriate antifungal or antibacterial agents. If a favorable response does not occur promptly, treatment should be withheld until the infection is adequately controlled.
4. If irritation occurs, stop treatment and start appropriate treatment. Allergic contact dermatitis to corticosteroids is usually diagnosed by observing a lack of improvement rather than clinical exacerbation. Confirm the observation with the appropriate diagnostic patch test.
5. The use of topical corticosteroids may increase the risk of posterior subcapsular cataracts and glaucoma. Cataracts and glaucoma have been reported in postmarketing experience with treatment. In case of eye contact, advise patients to report any visual symptoms and see an ophthalmologist for evaluation.
6. Epistaxis was observed more often in patients with allergic rhinitis and in patients with chronic rhinosinusitis with nasal polyps who were treated than in patients who received placebo.
7. In clinical studies, local infections of the nose and throat with Candida albicans have been reported. In case of infection, consumption should be stopped and appropriate local or systemic treatment should be given if needed.
8. Cases of perforation of the nasal septum have been reported following the use of corticosteroids in the nose. As with any long-term local treatment of the nasal cavity, patients treated for several months or more should be periodically examined for possible changes in the nasal mucosa.
9. Because of the inhibitory effect of corticosteroids on wound healing, patients who have recently experienced a septal ulcer, nasal surgery, or nasal trauma should not use nasal corticosteroids until healing.

Endocrine system effects of mometasone

1. Systemic absorption of topical corticosteroids can cause reversible suppression of the hypothalamic-pituitary-adrenal (HPA) axis with the potential for glucocorticosteroid failure.
2. Manifestations of Cushing’s syndrome, hyperglycemia and glucosuria can be induced in some patients by systemic absorption of topical corticosteroids during treatment.
3. Factors that predispose the patient to using topical corticosteroids to suppress the HPA axis include the use of high-strength steroids, a wide level of treatment, long-term use, the use of occlusive dressings, changes in the skin barrier, liver failure, etc.
4. Because of the potential for systemic absorption, using topical corticosteroids, patients should be periodically evaluated for HPA axis suppression.
5. Pediatric patients may be more susceptible to systemic toxicity than equivalent doses due to their larger skin surface area to body mass ratio.

Contraindications for mometasone ointment

Megacort ointment, like many drugs, has many contraindications and risks. If any of these cases are not observed, it will threaten the patient’s health and sometimes cause long-term side effects in patients. Therefore, before using Megacort ointment, carefully check the contraindications and cautions in its drug information.

1. Long-term use (without a doctor’s prescription)
2. Hypersensitivity
3. Recent nose surgery, nasal trauma, nasal septal ulcer (until healing occurs)

Side effects of Megacort (mometasone)

Itching, burning, acne rosacea, irritation, dry skin, acne-shaped pimples, secondary infection, etc. are some of the side effects of Megacort (Mometasone) ointment or spray. If any of these effects persist or worsen, tell your doctor or pharmacist right away. Most people who use this drug do not experience serious side effects.

If you have any serious side effects such as stretch marks, thinning or discoloration of the skin, acne, small red bumps on the skin (folliculitis), stop using the drug and consult your doctor. These side effects are more common in children and people who use this drug for a long time or on large areas of the skin.

1. Burning and itching
2. Acne rosacea
3. Blurred vision or cataracts
4. Secondary dryness or infection of the skin
5. folliculitis
6. Hypertrichosis
7. Acne-shaped pimples
8. Hypopigmentation
9. Allergic contact dermatitis
10. Atrophy of the skin
11. stretch marks
12. miliaria

Mometasone drug interactions

Drug interactions may change how your medications work or increase your risk of serious side effects. When patients go to the doctor, prepare a list of chemical and herbal medicines (including ointments, tablets and nasal sprays) and show them to him. Some drugs such as desmopressin, aldesluquin, logzapine, etc. have caused drug interactions with this product. Note that you should not use any ointment or cream with this product without a doctor’s prescription to avoid side effects and drug interactions.

Use of Megacort ointment (mometasone) during pregnancy and breastfeeding

No adequate clinical studies are available regarding the use of pregnant women and nursing mothers. In animal reproduction studies with pregnant rats, mometasone furoate increased fetal malformations and decreased fetal survival and growth following administration at doses that were approximately 1.3 to 8 times the maximum recommended human dose. However, experience with oral corticosteroids suggests that rodents are more susceptible to teratogenic and corticosteroid effects than humans. It should be noted that pregnant women and nursing mothers should not use any medicine without consulting a doctor.

The effect of mometasone nasal spray and ointment on breastfeeding

There is no information about the presence of the drug in human milk, its effects on the infant or milk production. Other corticosteroids are excreted in human milk, however, mometasone is minimally absorbed by the mother after systemic nasal administration, and breastfeeding is not expected to result in exposure of the infant to mometasone. The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for treatment and any possible side effects on the infant caused by medication or the mother’s underlying disease.

Storage conditions for mometasone ointment

Store Megacort ointment at room temperature and away from light and moisture. Keep medicinal products, both chemical and herbal, out of the reach of children and animals. Dispose of this product properly when it has expired or is no longer needed. If you intend to dispose of this medicine, do not pour the product into the sewer, toilet or street.

The last word about mometasone ointment

Based on what we said about this article from Positive Green Pharmacy magazine, Megacort Mometasone ointment is one of the best products in the field of skin care and treatment of skin problems. The special and efficient ingredients of this ointment have made it known as an effective solution in the treatment of skin inflammations, itching, eczema, skin secretions and other skin problems.

However, the use of any product has side effects. Before using Megacort Ointment or any other product, it is important to consult your doctor and follow the prescribed instructions. Also, in case of any complications or skin sensitivity, you should see a doctor and follow safety precautions.

Site source: Medscape