Bromhexine and its uses and side effects

By increasing the amount of mucus, bromhexine causes viscosity or a decrease in the overall thickness of sputum. This drug is widely used in the treatment of sputum diseases with severe cough such as corona. In this article, we intend to do a deep and comprehensive review of the drug Bromhexine and present its effects in the treatment of various diseases and disorders for the readers. This drug, with its unique combinations and suitable mechanisms of action, has greatly helped to improve the quality of life of many patients and facilitate the treatment for covered doctors.

Pharmaceutical forms of bromhexine

Bromhexine drug is recognized in the market under the brand names Bisolmed, Modalyte, Mucolin. This drug is produced and marketed in different forms including tablets, syrup and ampoule (injection solution). Due to the large number of manufacturing companies, this medicine is sold under different brand names such as Bromhexine 60 ml, Bisulex, Barkasin, Bisolon, Bromentol, Bethyl Bromhexine 60 syrup, Brofen Tunnel Plus, Bromax, Bromseal syrup, Disolon, Flamina, Mox, It is known as mucolin and…

Uses of bromhexine drug

Bromhexine is a mucolytic agent that reduces the thickness of sputum. This medicine is used to treat conditions such as colds, respiratory tract infections, and flu so that the patient can breathe freely and deeply. This drug should be used with caution in patients with a history of gastric ulcer due to the increased risk of serious side effects. Bromhexine improves mucus transport by reducing mucus viscosity and stimulating the ciliated epithelial layer (mucociliary clearance). Cough is relieved by secretory effects and secretion in the bronchial passages and sputum is expelled more easily.

Uses of Bromhexine in adults

1. Respiratory diseases such as bronchitis
2. Flu symptoms
3. pharyngitis
4. bronchitis
5. Flu symptoms
6. pharyngitis
7. bronchitis
8. Asthma
9. Polycystic lung diseases

Pharmacological effects and mechanism of action of Bromhexine drug

This drug is quickly absorbed through the digestive system and after one hour, it will reach the maximum plasma concentration. After being metabolized, the drug is excreted mainly through urine and to a limited extent through feces. Bromhexine works by reducing the viscosity of mucus and will be associated with increasing lysosomal activity. If lysosomal activity increases, the hydrolysis of acidic mucopolysaccharide polymers will be accelerated. This process can lead to normal mucus viscosity. The viscosity of the mucus in the bronchi increases if you have purulent inflammation of the bronchi, also the presence of a significant amount of DNA in the mucus is the basis of the mucus. Coughing may increase at first after taking this medicine because bromhexine breaks down mucus.

Dosage of Bromhexine tablets

Bromhexine is a drug that helps the body’s mucous cleansing processes in the respiratory system and is used to relieve chest congestion. This drug belongs to a class of drugs called mucolytics, which break up mucus to make coughing easier. As a result, to treat cough, this drug is added to cough syrups. The dosage of this drug is slightly different in different pharmaceutical forms, consult a doctor or pharmacist to know the dosage.

Time to use Bromhexine

In the pharmaceutical information available on the packaging of chemical and herbal medicines, the method of use and the time of use for general use are stated. If you are taking this drug without a prescription, you can use its drug information. Bromhexine tablets are usually taken three times a day after meals, along with plenty of fluids, and the syrup can be taken twice or four times a day. After use, if you feel better, continue taking the medicine. Because stopping the drug suddenly will increase the possibility of the disease returning.

Precautions

Before taking Bromhexine, if you are allergic to this drug or other ingredients in it, avoid using it. This medicine may contain some inactive ingredients that can cause some serious allergic reactions or some other problems. Patients with medical records such as gastric ulcer, asthma, kidney disease, stomach disease, liver or kidney failure, cardiovascular problems, severe chest pain, lung problems (such as breathing difficulties), etc. should take this medicine with caution and a doctor’s prescription.

1. Before taking this medicine, if you have a history of diseases such as stomach ulcer, asthma, kidney disease and severe liver or kidney failure, inform your doctor so that he can prescribe similar medicines for you if needed.
2. Patients who have disorders related to kidney or liver, should only take the medicine with a doctor’s prescription.
3. It should be used with caution in the first trimester of pregnancy, when planning to become pregnant, or during breastfeeding.
4. Symptoms of lung infection, such as difficulty in breathing while resting or sleeping and fever above 38°C, avoid consumption and consult a doctor.
5. If you have used this medicine for two weeks or more but you do not see any improvement in yourself, stop using the medicine and inform your doctor. After observing and examining the disease, the doctor will prescribe similar drugs.
6. If you have medical history such as gastric ulcer and gastrointestinal bleeding, take this medicine with plenty of water or with food.
7. Bromhexine ampoule should not be used in children under 12 years of age, unless the doctor determines that the benefits outweigh the risks of side effects.
8. Due to the increased risk of deterioration of the patient’s condition, this drug should be used with caution in patients with a history of liver diseases. In certain cases, depending on the clinical situation, close monitoring of liver function tests, reasonable dosage changes or substitution with an appropriate drug may be required.
9. Due to the increased risk of deterioration of the patient’s condition, the use of this drug is not approved in patients with a confirmed history of peptic ulcer or other gastrointestinal disorders. Any irregular symptoms should be reported to the doctor immediately. Depending on the clinical condition of the patient, it may be necessary to change the appropriate dose or replace it with a suitable drug.

Bromhexine side effects

Ear irritation, throat infection, skin rash, headache, diarrhea and vomiting are some of the side effects of Bromhexine. If any of these side effects get worse, stop taking the medicine and see a doctor. Many patients who take this drug do not experience side effects. Some of the serious side effects of this drug include severe chest pain, severe and prolonged cough, frequent and severe sore throat, pain in the stomach and abdomen, constipation or severe diarrhea, etc. If these dangerous side effects occur, stop taking the drug.

1. ear irritation
2. skin rash
3. Dizziness and headache
4. nausea and vomiting
5. diarrhea
6. Difficulty breathing
7. rush
8. Respiratory tract infection
9. throat infection

Drug interaction of bromhexine

No dangerous drug interactions have been reported. However, avoid taking multiple medications at the same time as bromhexine.

Taking Bromhexine during pregnancy and breastfeeding

The use of bromhexine during pregnancy (especially the first 3 months of pregnancy) is not recommended, unless its benefits outweigh the risk of side effects for the fetus and mother. Before taking this medicine, talk to your doctor about all its side effects and benefits. Also, this drug is not used during breastfeeding, because it can be transferred to breast milk and cause serious side effects for babies. If you use Bromhexine while breastfeeding, stop breastfeeding.

What is the difference between diphenhydramine and bromhexine?

Bromhexine is a mucolytic agent that reduces the thickness of sputum. This drug is used to treat diseases characterized by abnormal mucus secretion, such as colds and respiratory tract infections. On the other hand, diphenhydramine syrup is used to treat cough and relieves allergy symptoms such as runny nose, stuffy nose, sneezing, watery eyes and congestion or cough. Bromhexine is a drug that helps the body’s mucous cleansing processes in the respiratory system. It is also used to relieve chest congestion.

Bromhexine storage conditions

Direct contact with heat, air, and light may damage bromhexine medications. The drug should generally be stored at room temperature between 68°F and 77°F (20°C and 25°C). Also, keep all medicines out of the reach of children and animals.

The last word about the drug bromhexine

In this article, we introduced and reviewed the drug bromhexine and examined its effects and applications in improving human health and reducing cough symptoms. Nevertheless, it is necessary to pay attention to points such as the limitations and possible side effects of Bromhexine and always prescribe and use it under the supervision of a doctor. Some of the side effects of this medicine include ear irritation, skin rash, diarrhea, nausea and vomiting, headache and dizziness, throat infection, upper tract infection, etc. This content is a summary of Bromhexine drug from Positive Green Online Pharmacy magazine that we described for you.

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