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What is atropine eye drops for?

Atropine or Myopin eye drops, as the name suggests, are available in liquid form and in the form of drops, and are most commonly used to dilate the pupil of the eye before an eye examination by an ophthalmologist. Also, Myopin (atropine) drops can be used to treat some eye diseases. Stay with us for more information about this drug in this article.

What we read in this article

What is atropine drop?

Atropine sulfate eye drops are used to dilate the pupil of the eye before an eye examination. They also use this drop to treat amblyopia or lazy eye, cycloplegia, etc. This drug works by blocking the chemical acetylcholine, which relaxes the ciliary muscle of the eye and causes the pupil to dilate. You are allowed to consume and buy Myopin drops only with a doctor’s prescription.

Pharmaceutical forms of atropine

Atropine in the form of drops is used to treat vision problems and before eye examinations, but atropine tablets or ampoules that you may see in pharmacies or are prescribed to you have other uses; such as relieving muscle spasms of the digestive tract or treating irritable bowel syndrome. Ophthalmic atropine is available in two dosage forms:

Uses of atropine eye drops (Myopin)

Atropine eye drops are used in the following cases:

  • Pupil dilation before eye examination
  • Treatment of an eye disease called amblyopia (lazy eye)
  • Treatment of other eye diseases such as cycloplegia

Atropine is also used to treat bradycardia, control some digestive disorders such as irritable bowel syndrome or biliary colic, and as a pre-anesthesia drug to reduce salivary and respiratory secretions.

Pharmacological effects and mechanism of action of Atropine drops

Atropine is an anticholinergic drug that works by blocking the action of the neurotransmitter acetylcholine. By blocking muscarinic receptors, this drug inhibits the effects of acetylcholine and leads to an increase in heart rate, relaxation of smooth muscles, reduction of secretions, and dilation of the pupils.

Dosage of Atropine eye drops

The dose of atropine eye drops can be different depending on the specific indication and the age, weight and medical condition of the patient, so it should be determined by the doctor for each person separately. But in general, the consumption amount is as follows:

  • In adults and children over 3 months: 1 drop 40 minutes before the eye examination by a doctor.

If this drop should be used for other purposes and has a therapeutic aspect, the dose and frequency of use must be determined by an ophthalmologist.

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How to use atropine drops

This medication is formulated for intraocular use only. Pay attention to the following when using Myopin eye drops:

  • Wash your hands before and after using this drop.
  • Tilt your head back and pull your lower eyelid down with your index finger.
  • Pour the required number of drops into your eye as prescribed by the doctor.
  • Do not blink for 30 seconds. Close your eyes gently to let the drops spread.


  • Atropine eye drops may cause drowsiness, dizziness, or blurred vision.
  • Avoid activities that require full alertness while using this medicine. like driving
  • High doses of atropine or its long-term use may have serious side effects; Therefore, consult a doctor in this regard.
  • Before using this drop, inform your doctor if you are pregnant, breastfeeding, allergic to certain medications, or suffering from hemorrhoids.
  • If you forget to take this drop, use it as soon as you remember. If the time of the next appointment is close, use only the same dose of the medicine and do not double it.
  • If you have a heart problem, digestive disorder or glaucoma, be sure to inform your doctor.
  • It is not recommended to use this drop in children under 3 months; unless advised by a doctor.
  • Elderly people should use this drop with more caution because they may be more sensitive.

Contraindications for atropine eye drops

  • People who are allergic to atropine or its components should not use it.
  • People suffering from glaucoma, urinary retention, obstructive disorders of the digestive system or cardiac arrhythmia should use this drop with caution and under the supervision of a doctor.
  • People addicted to alcohol or tobacco should not use this medicine.

Atropine drops for lazy eye

Atropine eye drops side effects

The following can be among the side effects of atropine eye drops (Myopin):

  • Dry mouth and throat
  • Dizziness or lightheadedness
  • Blurred vision and increased sensitivity to light
  • Eye pain or eye irritation
  • Night vision problem
  • Urinary retention
  • constipation
  • Confusion or memory problems
  • increase of heart rate

Drug interactions of atropine eye drops

Before using atropine eye drops, let your doctor know about any medications, supplements, or vitamins you are taking. Pay attention to the following:

  • Atropine may interact with drugs that have anticholinergic effects, such as antihistamines, tricyclic antidepressants, and antipsychotics, and increase the risk of their side effects.
  • Drugs that have pro-arrhythmic effects may increase the risk of cardiac arrhythmia if taken concurrently with atropine.
  • Some other drugs that can interact with atropine eye drops are: ambenonium, potassium, amifampridine, bupropion, clozapine, donepezil, glucagon, glycopyrrolate, glycopyrronium tosylate, mackimorelin, methacholine, rufenacin, scopolamine, tiotropium.

This list is not complete and you should inform your doctor about any type of medication you are using to prevent drug interactions.

Use of atropine eye drops during pregnancy and breastfeeding

  • In general, it can be said that the use of atropine eye drops (Mayopin) during pregnancy is safe, however, you must consult a doctor before using it.
  • Research has shown that atropine is excreted in very small amounts through breast milk. However, there is no contraindication for this drop during breastfeeding, but it is recommended to consult a doctor before use.

Atropine drop storage conditions

  • Store atropine eye drops in a closed container at room temperature, away from heat, moisture and direct light.
  • It is not forbidden to put this drop in the refrigerator.
  • Prevent this drop from freezing.

A final word about atropine drops

In this article from the online pharmacy magazine Positive Green, we examined atropine eye drops (Myopin). Above all, this drop is used to dilate the pupil of the eye before an eye examination, and it also helps to treat some eye diseases such as lazy eye. You are not allowed to use this medicine without a doctor’s prescription. In order to avoid drug interactions, if you are using a certain drug, be sure to consult your doctor before starting to use this drop.

Site source: Medscape

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